However this is hard to achieve due
to contributing factors to be taken into account such as annual leave,
sickness, change of job or transfer of staff to other departments
within the hospital. So to retain this high level of performance in
reality is extremely difficult.
Let us say we assume that we already
have good dedicated Anticoagulation Care in place. From the Randomised
Study (Ref, Poller et al, The Lancet, vol, 352 no.9139 pages
1505-1509) Dawn AC achieved 20% to 30% better INR control in terms
of our algorithm.
In the trial the percentage of INR’s for the
computer dosed patients was 15% above range and for the manually dosed
patients 17%.
It could therefore be concluded that there is
(17-15)/17X100= 11% reduction in the number of times a patient enters
the high INR ranges which can lead to increased bleeding opportunity.
Note, most of the gain from the computer system was in preventing low INR’s and so possibly preventing thrombo-embolic events.
This would equate to:
